Production of squalene from genetically engineered poplar tree leaves

Date:July 9, 2024

Plant Name:

    Poplar

Residue Name:

    Leaves

End Products

Biochemicals

cosmetics

Food

food supplements

Application

  • The genetically engineered poplar trees producing squalene have applications in the production of cosmetics, pharmaceuticals, and food supplements.

Description

Researchers have successfully genetically engineered poplar tree leaves to produce significant amounts of squalene, a highly valued chemical compound. Squalene is commonly used in the production of cosmetics, pharmaceuticals, and food supplements due to its moisturizing and antioxidant properties. Traditionally, squalene has been sourced from shark liver oil, which is expensive and raises environmental concerns, or from olives, which yield limited quantities. By harnessing the genetic potential of poplar trees, scientists aim to create a more sustainable, efficient, and cost-effective method for producing squalene, paving the way for its increased use in various industries.

Pathway Description:

Researchers used two processes—cytosol-based production and chloroplast-based production—to engineer poplar trees for squalene synthesis. The chloroplast pathway yielded 0.63 milligrams of squalene per gram of leaves, outperforming the cytosol pathway. Economic analysis suggested boosting production or converting squalene into higher-value compounds like ambrein for feasibility. This innovation provides a sustainable alternative to shark-derived squalene and reduces greenhouse gas emissions.

Source: Know More...

Tags: Genetic modification of poplar treeSqualene from poplar treeSustainbale squalene

End Products

Biochemicals

cosmetics

Food

food supplements

Feedstock

Types of Feedstock

Forest residue

Name

Poplar tree leaves

Form

Solid biomass

Logistics

Renewable non-food crop; grown on non-agricultural land

Pathways

Biological

Cytosol-based production,Chloroplast-based production

Stakeholders

Educational Institution

Michigan State University