Date:July 5, 2019
Country: United States
Plants
Trees
Lignin
Biomaterials
bioplastics
Biochemicals
acetaminophen
Medicine
Pharmaceutical Production
Application
Description Researchers at the University of Wisconsin-Madison have developed a patented method to synthesize acetaminophen, the active ingredient in Tylenol, from lignin, a complex polymer found in plant cell walls. This renewable process offers an alternative to the fossil fuel-based production of acetaminophen and utilizes a molecule naturally present in plants like poplar. The method not only provides a sustainable source for the medication but also enhances the economics of biorefineries by creating valuable side products.
Pathway Description: The process for converting lignin into acetaminophen involves isolating p-hydroxybenzoate, a naturally occurring molecule attached to lignin in plants like poplar. This molecule is extracted as a pure stream during a biomass pretreatment process. Researchers then employ a series of short, cost-effective chemical reactions to transform p-hydroxybenzoate into acetaminophen. This method leverages the inherent structure of plant-derived molecules, making it a renewable and sustainable alternative to traditional fossil-fuel-based synthesis. 4o
Source: Know More...
Tags: Lignin-Based AcetaminophenBio-based ChemicalsRenewable Pharmaceutical Production
Biomaterials
bioplastics
Biochemicals
acetaminophen
Medicine
Pharmaceutical Production
Types of Feedstock
Secondary agricultural residue
Name
Lignin
Form
Solid biopolymer
Commercials
Low-cost and renewable
Characteristics
Complex structure rich in aromatic compounds
Educational Institution
University of Wisconsin-Madison