Sesaminol: A Potential Parkinson’s Treatment With seasame seeds

Date:March 5, 2021

Country: Japan

Application

• Potential preventive treatment for Parkinson’s disease through antioxidant properties of sesaminol.
• Neuroprotective therapy to reduce oxidative stress and dopamine loss in Parkinson’s patients.

Description

This project investigates the potential of sesaminol, an antioxidant found in sesame seed husks, as a preventive treatment for Parkinson's disease. The compound was shown to protect nerve cells from oxidative damage in laboratory cultures and improve motor function in a mouse model of Parkinson’s. Researchers suggest that sesaminol could help reduce dopamine loss and prevent disease progression. Clinical trials are needed to confirm its effectiveness in humans.

Pathway Description:

Sesaminol is produced from the husks of sesame seeds, which are a waste product of sesame oil extraction. The husks contain a high concentration of sesaminol, an antioxidant compound. After extracting the oil from the sesame seeds, the husks are processed to isolate sesaminol. This compound is then tested for its potential neuroprotective properties against Parkinson’s disease.