Palm Kernel Shells Derived Carbon Quantum Dots for Inflammation Imaging

Date:3 June 2024

Country: Japan Malaysia

Application

• Bioimaging: Carbon quantum dots (CQDs) are used for visualizing inflammation in various cell lines and models.
• Theragnostics: CQDs help modulate inflammatory markers, offering potential for targeted therapies in immune-related diseases.

Description

This project focuses on the synthesis of biomass-derived carbon quantum dots (CQDs) from palm kernel shells as eco-friendly alternatives to traditional quantum dots. The CQDs are evaluated for their potential as non-toxic bioimaging agents, capable of visualizing inflammation and modulating inflammatory markers in various cell lines. The study demonstrates their application in precision medicine, with potential as theragnostic agents for immune system-related diseases. The CQDs are synthesized using a simple hydrothermal method, offering a sustainable and cost-effective approach.

 

 

Pathway Description:

The project uses a hydrothermal method to synthesize carbon quantum dots (CQDs) from biomass waste, specifically palm kernel shells. The process involves mixing the biomass with citric acid and ethylenediamine(chemical cross-linking), followed by heating at 160°C for 4 hours. The resulting CQDs are purified through filtration and dialysis, then freeze-dried for further use. This eco-friendly method enables the production of CQDs with potential applications in bioimaging and inflammation modulation.