Electro-Fermentation for Organic Acids

Introduction Organic acids like lactic acid, acetic acid, succinate, and propionate are key platform chemicals used in bioplastics, food additives, pharmaceuticals, and chemical synthesis. Conventionally produced via fermentation, their yields and productivity are...

Sustainable Pathways for Biobased Terephthalic Acid

Introduction Terephthalic acid (TPA) is a cornerstone of the global plastics industry, serving as the key monomer in polyethylene terephthalate (PET) used for bottles, fibers, textiles, and films. Conventionally, TPA is derived from paraxylene, a fossil-based aromatic...

Synthetic Biology for Biobased Polyisoprene

Introduction Polyisoprene is the primary polymer in natural rubber, extensively used in tires, footwear, medical gloves, adhesives, and automotive components. Traditionally sourced from the rubber tree (Hevea brasiliensis), natural rubber is constrained by climatic...

Microbial Production of Muconic Acid

Introduction Muconic acid is an unsaturated dicarboxylic acid with immense industrial value. It serves as a precursor for adipic acid, terephthalic acid, caprolactam, and nylon derivatives, making it a vital platform chemical for bioplastics, synthetic fibers,...

Biocatalytic Synthesis of Itaconic Acid Derivatives

Introduction Itaconic acid is a renewable unsaturated dicarboxylic acid produced by fermentation of sugars, especially by Aspergillus terreus and engineered strains of Ustilago maydis or E. coli. Recognized by the U.S. Department of Energy as a top biobased platform...

Metabolic Engineering for Renewable Propylene Glycol

Introduction Propylene glycol (PG) is a widely used chemical intermediate in industries like cosmetics, pharmaceuticals, food, plastics, and antifreeze. Conventionally derived from petroleum-based propylene oxide, its production contributes to fossil fuel consumption...