Microbial Conversion of Biomass to Itaconic Acid

Introduction Itaconic acid (IA) is a promising bio-based platform chemical used in the production of biodegradable plastics, resins, adhesives, coatings, and superabsorbent polymers. Traditionally derived via fermentation, itaconic acid has been identified by the U.S....

Bio-based Production of Succinonitrile

Introduction Succinonitrile (SN) is a versatile organic compound characterized by two nitrile groups attached to a four-carbon backbone. It serves as a critical intermediate in pharmaceutical synthesis, polymer manufacturing, and as a solid electrolyte additive in...

Fermentative Production of Biobased Acetone

Introduction Acetone is a key industrial solvent used in plastics, paints, pharmaceuticals, and cosmetics, traditionally derived from petroleum-based processes like cumene oxidation. However, rising interest in biobased chemicals has revived research into its...

Enzyme-Driven Pathways for Gluconic Acid

Introduction Gluconic acid is a mild organic acid derived from the oxidation of glucose, known for its non-toxic, biodegradable nature and broad applications in food, pharmaceuticals, textiles, construction, and cleaning agents. Traditionally produced via microbial...

Metabolic Engineering of Microbes for Terpene Production

Introduction Terpenes are a diverse class of hydrocarbons built from isoprene units (C₅H₈), forming the backbone of many bioactive compounds, flavors, fragrances, pharmaceuticals, and even biofuels. Naturally produced by plants and some microbes, terpenes such as...